We study the thermodynamics of two flavor color superconducting (2SC) quark matter within a nonlocal chiral quark model, using both instantaneous and covariant nonlocal interactions. For applications to compact stars, we impose conditions of electric and color charge neutrality as well as β equilibrium and construct a phase transition to the hadronic matter phase described within the Dirac-Brueckner-Hartree-Fock (DBHF) approach. We obtain mass-radius relations for hybrid star configurations which fulfill modern observational constraints, including compact star masses above 2M_o.