Página Inicial CNEA Laboratorio TANDAR Página Inicial TANDAR Historia del acelerador TANDAR Web interno Web mail
Inicio » Actividades I+D > Publicaciones 2014 >  9Be(d,n)10B-based neutron sources for B...
acta de conferencia
" 9Be(d,n)10B-based neutron sources for BNCT"
M.E. Capoulat, M.S. Herrera, D.M. Minsky, S.J. González and A.J. Kreiner
Proc. of the "15th International Congress on Neutron Capture Therapy" (15-ICNCT), Tsukuba, Japan, September 10-14, 2012. Ed. by A. Matsumura, T. Yamamoto, K. Nakai and H. Kumada
Appl. Radiat. Isot. 88 (2014) 190-194
In the frame of accelerator-based BNCT, the 9Be(d,n)10B reaction was investigated as a possible source of epithermal neutrons. In order to determine the configuration in terms of bombarding energy, target thickness and Beam Shaping Assembly (BSA) design that results in the best possible beam quality, a systematic optimization study was carried out. From this study, the optimal configuration resulted in tumor doses ≥40 Gy-Eq, with a maximum value of 51 Gy-Eq at a depth of about 2.7 cm, in a 60 min treatment.
The optimal configuration was considered for the treatment planning assessment of a real Glioblastoma Multiforme case. From this, the resulted dose performances were comparable to those obtained with an optimized 7Li(p,n)-based neutron source, under identical conditions and subjected to the same clinical protocol.
Av. Gral Paz y Constituyentes, San Martín, Pcia. de Buenos Aires, Argentina
Tel: (54-11) 6772-7007 - Fax: (54-11) 6772-7121