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artículo con referato
"Lamotriginium crotonate and lamotriginium salicylate ethanol monosolvate: The role of solvent molecules in the packing organization"
E. Freire, G.A. Echeverría and R. Baggio
Acta Cryst. C 73(7) (2017) 563-568
Two lamotriginium salts, namely lamotriginium crotonate [systematic name: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazin-2-ium but-2-enoate, C9H8Cl2N5+·C4H5O2-, (III)] and lamotriginium salicylate [systematic name: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazin-2-ium 2-hydroxybenzoate ethanol monosolvate, C9H8Cl2N5+·C7H5O3-·C2H5OH, (IV)] present extremely similar centrosymmetric hydrogen-bonded ALLA packing building blocks (L is lamotriginium and A is the anion). The fact that salicylate salt (IV) is (ethanol) solvated, while crotonate salt (III) is not, has a profound effect on the way these elemental units aggregate to generate the final crystal structure. Possible reasons for this behaviour are analyzed and the hypothesis raised checked against similar structures in the literature.
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